Uridine triphosphate 495471 218335528 2008-06-10T04:45:08Z Arcadian 104523 nav {{Chembox new | ImageFile = Uridintriphosphat2.svg | ImageSize = | IUPACName = | OtherNames = | Section1 = {{Chembox Identifiers | CASNo = 63-39-8 | PubChem = 1181 | SMILES = | MeSHName = Uridine+triphosphate }} | Section2 = {{Chembox Properties | Formula = C<sub>9</sub>H<sub>15</sub>N<sub>2</sub>O<sub>15</sub>P<sub>3</sub> | MolarMass = 484.141 | Appearance = | Density = | MeltingPt = | BoilingPt = }} | Section3 = {{Chembox Hazards | Solubility = | MainHazards = | FlashPt = | Autoignition = }} }} '''Uridine triphosphate''' is a [[pyrimidine]] [[nucleotide]], consisting of the [[organic base]] [[uracil]] linked to the 1' carbon atom of the sugar [[ribose]], esterified with tri-[[phosphoric acid]] at its 5'-position. Its main role is as substrate for the synthesis of [[RNA]] during [[transcription (genetics)|transcription]]. UTP also has the role of a source of energy or an activator of substrates in metabolic reactions, like that of [[Adenosine Triphosphate|ATP]], but more specific. When UTP activates a substrate, UDP-substrate is usually formed and inorganic phosphate is released. UDP-glucose enters the synthesis of [[glycogen]]. UTP is used in the metabolism of [[galactose]], where the activated form UDP-galactose is converted to UDP-glucose. UDP-[[glucuronate]] is used to conjugate [[bilirubin]] to a more water soluble [[bilirubin diglucuronide]]. ==See also== * [[CTP synthase]] {{Nucleobases, nucleosides, and nucleotides}} [[Category:Nucleotides]] [[Category:Pyrimidines]] [[Category:Gene expression]] [[Category:Metabolism]] {{biochem-stub}} [[da:Uridintrifosfat]] [[de:Uridintriphosphat]] [[ja:ウリジン三リン酸]] [[zh:三磷酸尿苷]] [[it:Uridintrifosfato]]