Venous thrombosis 211191 222333765 2008-06-28T19:54:54Z DOI bot 6652755 Citation maintenance. Added: pmid, doi. Formatted: pages. You can [[WP:DOI|use this bot]] yourself! Please [[User:DOI_bot/bugs|report any bugs]]. {{Infobox_Disease | Name = {{PAGENAME}} | Image = | Caption = | DiseasesDB = | ICD10 = {{ICD10|I|80||i|80}}-{{ICD10|I|82||i|80}} | ICD9 = {{ICD9|453}} | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = D020246 | }} A '''venous thrombosis''' is a [[blood clot]] that forms within a [[vein]]. ([[Thrombosis]] is a specific medical term for a blood clot that remains in the place where it formed.) ==Classification== ''Superficial venous thromboses'' can cause discomfort but generally do not cause serious consequences, unlike the ''[[deep venous thrombosis|deep venous thromboses]]'' (DVTs) that form in the deep veins of the legs or in the pelvic veins. Since the veins return [[blood]] to the [[heart]], if a piece of a blood clot formed in a vein breaks off it can be transported to the right side of the heart, and from there into the [[lung]]s. A piece of thrombus that is transported in this way is an ''[[embolism]]'': the process of forming a thrombus that becomes embolic is called a ''thromboembolism''. An embolism that lodges in the lungs is a ''[[pulmonary embolism]]'' (PE). A pulmonary embolus is a very serious condition that can be fatal if not recognized and treated promptly. Systemic embolisms of venous origin can occur in patients with an [[Atrial septal defect|atrial]] or [[ventricular septal defect]], through which an embolus may pass into the arterial system. This is termed a [[paradoxical emboli]]. ==Risk factors== *'''General''' **Older age **Female gender **Smoking **Obesity **Pregnancy **Immobilisation **Minor injuries<ref name=Stralen>{{cite journal | volume= 168 No. 1|date= January 14, 2008 |title=Minor Injuries as a Risk Factor for Venous Thrombosis |author=Karlijn J. van Stralen, MSc; Frits R. Rosendaal, MD, PhD; Carine J. M. Doggen, PhD |url=http://archinte.ama-assn.org/cgi/content/short/168/1/21 |journal=Arch Intern Med|pages=21–26 |pmid=18195191 |doi=10.1001/archinternmed.2007.5}}</ref> *'''Medical''' **[[Surgery]] **[[Trauma]] **[[Oral contraceptive]] use **[[Varicose veins]] **[[Malignancy]] **[[Kidney disorder]]s **[[Lupus anticoagulant]] **[[Paroxysmal nocturnal hemoglobinuria]] **[[Inflammatory bowel disease]] **[[Thromboangiitis obliterans]] (Mb Bürger) **[[Disseminated intravascular coagulation]] *'''Familial''' **[[Antithrombin|Antithrombin III deficiency]] **[[Protein C deficiency]]/[[Protein S deficiency]] **APC resistance ([[Factor V Leiden]]) **[[Dysfibrogenemia]] **[[Hypoplasminogenemia]] **Familial [[homocysteinemia]] ==Prevention== [[Tocopherol|Vitamin E]] may prevent venous thrombosis.<ref name="pmid17846285">{{cite journal |author=Glynn RJ, Ridker PM, Goldhaber SZ, Zee RY, Buring JE |title=Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study |journal=Circulation |volume=116 |issue=13 |pages=1497–503 |year=2007 |pmid=17846285 |doi=10.1161/CIRCULATIONAHA.107.716407}}</ref> ==References== <references/> ==See also== * [[Portal vein thrombosis]] * [[Deep vein thrombosis]] * [[Pulmonary embolism]] * [[Arterial thrombosis]] * [[Plethysmography]], a test to detect a venous thrombosis {{Vascular diseases}} [[Category:Hematology]] [[ja:静脈血栓塞栓症]] [[pt:Trombose venosa]]