Virchow's node 732432 223048213 2008-07-02T10:04:30Z DOI bot 6652755 Citation maintenance. Formatted: title. You can [[WP:DOI|use this bot]] yourself! Please [[User:DOI_bot/bugs|report any bugs]]. {{Infobox Lymph | Name = {{PAGENAME}} | Latin = | GraySubject = 177 | GrayPage = 697 | Image = Lymph node regions.jpg | Caption = Regional lymph tissue. (Supraclavicular near top, in green.)⋅ | Image2 = Illu lymph chain02.jpg | Caption2 = '''Deep Lymph Nodes'''<BR>1. Submental<BR>2. Submandibular (Submaxillary)<BR><BR>'''Anterior Cervical Lymph Nodes (Deep)'''<BR>3. Prelaryngeal<BR>4. Thyroid<BR>5. Pretracheal<BR>6. Paratracheal<BR><BR>'''Deep Cervical Lymph Nodes'''<BR>7. Lateral jugular<BR>8. Anterior jugular<BR>9. Jugulodigastric<BR><BR>'''Inferior Deep Cervical Lymph Nodes'''<BR>10. Juguloomohyoid<BR>11. Supraclavicular (scalene) | DrainsFrom = | DrainsTo = | MeshName = | MeshNumber = | DorlandsPre = n_09 | DorlandsSuf = 12575322 | }} In [[medicine]] ([[oncology]]), '''Virchow's node''' (or '''signal node''') is an enlarged, hard, left [[clavicle|supraclavicular]] [[lymph node]] which can contain [[metastasis]] of visceral (abdominal) [[malignancy]]. ==Clinical significance== Malignancies of the internal organs can reach an advanced stage before giving symptoms. [[Stomach cancer]], for example, can remain [[symptom]]less while [[metastasis|metastatizing]]. One of the first visible spots where these tumors metastatise is the left supraclavicular lymph node. The left supraclavicular node is the classical Virchow's node because it is on the left side of the neck where the [[lymphatic system|lymphatic]] drainage of most of the body (from the [[thoracic duct]]) enters the venous circulation via the left [[subclavian vein]]. [[Differential diagnosis]] of an enlarged Virchow's node includes [[lymphoma]], various intra-abdominal malignancies, [[breast cancer]], [[lung cancer]], and [[infection]] (e.g. of the arm). ==Eponym== It is named after [[Rudolf Virchow]] ([[1821]]-[[1902]]), the [[Germany|German]] [[pathology|pathologist]] who first described the association. The presence of an enlarged Virchow's node is also referred to as '''[[Troisier's sign]]''', named after Charles Emile Troisier, who also described this. Because an enlarged Virchow's node is often a harbinger of malignant disease, it is sometimes called the ''sentinel node''. This needs to be contrasted with the technique of [[sentinel lymph node]] biopsy. It should also not be confused with the 'sentinel gland' of the [[greater omentum]].<ref>{{eMedicineDictionary|sentinel+gland}}</ref> ==Additional images== <gallery> Image:Gray602.png|Superficial lymph glands and lymphatic vessels of head and neck. </gallery> ==References== <references/> ==External links== * {{WhoNamedIt|synd|1222}} * {{GPnotebook|1973026851}} * {{FPnotebook|HEM39}} * {{cite journal | author = Mizutani M, Nawata S, Hirai I, Murakami G, Kimura W | title = Anatomy and histology of Virchow's node | journal = Anat Sci Int | volume = 80 | issue = 4 | pages = 193–8 | year = 2005 | pmid = 16333915 | doi = 10.1111/j.1447-073X.2005.00114.x}} {{med-sign-stub}} {{Lymphatics of head and neck}} [[Category:Lymphatic system]] [[es:Nódulo de Virchow]]