Sang de cordon 571577 26134544 2008-02-13T02:06:09Z DumZiBoT 280295 Robot : Passage au modèle {{ébauche}} : {{ébauche|médecine}} ; changement de type cosmétique {{ébauche|médecine}} Le '''sang de cordon''' est du [[sang]] humain du [[placenta]] et du [[cordon ombilical]], qui est laissé après la [[naissance]]. Le sang de cordon est prélevé après que le cordon ombilical ait été détaché du [[nouveau-né]]. Le sang de cordon est conservé dans le but d'utiliser les [[Cellule souche (médecine)|cellules-souches]] qu'il contient. == Propriétés == Les cellules-souches du sang de cordon prolifèrent plus et ont une plus grande chance de correspondre à des membres de la famille que celles de la [[moelle osseuse]]. Les pères ont 25 % de probabilité de correspondance avec les cellules-souches du sang de cordon de leur enfant. == Prélévement, stockage et coûts == <!-- Cord blood is collected after the placenta is delivered and the umbilical cord is clamped off from the newborn. The placenta is placed in a [[sterile]] supporting structure with the umbilical cord hanging through the support. The cord blood is collected by gravity drainage yielding an average of 99 mL, or is withdrawn from the umbilical vein. At public cord blood banks, this blood is then analyzed for infectious agents and the tissue-type is determined. Cord blood is processed and depleted of red blood cells before being stored in [[liquid nitrogen]] for later use. New parents have the option of storing their newborn's cord blood at a private [[cord blood bank]] or donating it to a public cord blood bank. The cost of private cord blood banking is approximately $2000 for collection and approximately $100 per year for storage as of 2005. The donation of cord blood is not available in all areas and often the [[Obstetrics and gynaecology|OB/GYN]] will still charge a collection fee of $100-$250, which is not covered by insurance. "According to research in the Journal of Pediatric Hematology/Oncology (1997, 19:3, 183-187), the odds that a child will need to use his or her own stem cells by age twenty-one for current treatments are about 1:2,700, and the odds that a family member would need to use those cells are about 1:1,400." [http://www.cordblood.com/cord_blood_banking_with_cbr/common_misconceptions/index.asp source] In 2005, [[University of Toronto]] researcher Peter Zandstra developed a method to increase the yield of cord blood stem cells to enable their use in treating adults as well as children.[http://www.news.utoronto.ca/bin6/051014-1723.asp] For more information on cord blood banking, see [[cord blood bank]]. --> == Utilisation == <!-- When [[Cryopreservation|cryopreserved]] cord blood is needed, it is thawed, washed of the cryoprotectant, and injected through a vein of the patient. This kind of treatment, where the stem cells are collected from another donor, is called [[allogeneic treatment]]. When the cells are collected from the same patient on whom they will be used, it is called [[autologous treatment|autologous]] and when collected from identical individuals, it is referred to as syngeneic. [[Xenogeneic treatment|Xenogeneic]] transfer of cells (between different species) is very underdeveloped and is said to have little research potential. --> == Maladies traitées avec du sang de cordon == ''Cette section est en travaux'' Dès la fin des [[années 1980]], les cellules-souches de sang de cordon ont été utilisées pour traiter de nombreuses [[maladie génétique|maladies génétiques]], [[cancer]]s, et hémopathies. Cela concerne à l'heure actuelle environ 75 maladies, parmi lesquelles : {| border="1" cellpadding="4" cellspacing="0" style="margin: 0.5em 1em 0.5em 0; background: #f9f9f9; border: 1px #aaa solid; border-collapse: collapse; font-size: 95%; width:100%" !A-D !E-L !M-Z |- | valign="top" | *[[Adrénoleucodystrophie]] *[[Métaplasie agnogénique myéloïde]] *[[Thrombocytopénie amégacaryocytique]] [http://marrowfailure.cancer.gov/AMEGA.html] *[[Amyloïdose]] *'''[[Anémie]]s :''' **[[Anémie aplasique]] **[[Anémie de Blackfan-Diamond]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Anemia%2C%20Blackfan%20Diamond] **[[Anémie congénitale dysérythropoïétique]] **Anémie de Cooley (Beta-[[thalassémie]] majeure) **[[Anémie de Fanconi]] **[[Anémie réfractaire]] [http://www.medterms.com/script/main/art.asp?articlekey=5275] **[[Anémie aplasique grave]] [http://www.marrow.org/PATIENT/aplastic_anemia.html] **[[Drépanocytose]] *[[Aspartylglucosaminurie]] [http://www.mannosidosis.org/aspartyl/aspclinic.htm] *[[Cytopénie]] congénitale *'''[[Cancer]]s :''' **[[Tumeur du cerveau|Tumeurs du cerveau]] **[[Sarcome d'Ewing]] **[[Myélome multiple]] **[[Neuroblastome]] **[[Cancer de l'ovaire]] **[[Carcinome à cellules rénales]] **[[Cancer du poumon]] à petites cellules **[[Cancer des testicules]] **[[Macroglobulinémie de Waldenström]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Waldenstrom%27s%20Macroglobulinemia] *[[Syndrome de Chediak-Higashi]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Chediak%20Higashi%20Syndrome] *[[Microdélétion 22q11]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=DiGeorge%20Syndrome] *[[Dyskératose congénitale]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Dyskeratosis%20Congenita] | valign="top" | *[[Syndrome d'Evan]] [http://www.madisonsfoundation.org/content/3/1/display.asp?did=81] *[[Thrombasthénie de Glanzmann]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Glanzmann%20Thrombasthenia] *[[Maladie de Gunther]] *[[Syndrome de Hunter]] *[[Syndrome de Hurler]] *[[Syndrome de Kostmann]] [http://www.medicinenet.com/script/main/art.asp?articlekey=8781] *[[Maladie de Krabbe]] *[[Histiocytose des cellules de Langerhans]] [http://www.royalmarsden.nhs.uk/clinicalservices/clinicalunits/paediatric/booklets/lch.asp] *[[Syndrome de Lesch-Nyhan]] *'''[[Leucémie]]s :''' **[[Leucémie aiguë biphénotypique]] [http://www.medicalhosting.org/archives/FMPro?-db=backissues.fp5&-format=details.html&-lay=show&PMID=9107085&-find=] **[[Leucémie aiguë lymphocytaire]] **[[Leucémie aiguë myéloblastique]] **Leucémie aiguë non différenciée **[[Leucémie chronique lymphocytaire]] **[[Leucémie chronique myéloblastique]] **[[Leucémie chronique myélomonocytaire]] [http://ghr.nlm.nih.gov/ghr/glossary/chronicmyelomonocyticleukemia] **[[Leucémie chronique myéloblastique]] juvénile [http://www.jco.org/cgi/content/abstract/5/12/1960] **[[Leucémie juvénile myélomonocytaire]] [http://www.cancerhelp.org.uk/help/default.asp?page=5729] **[[Leucémie à plasmocytes]] [http://www.biomedcentral.com/1527-2729/2/205/abstract] **[[Leucémie prolymphocytaire]] [http://www.thedoctorsdoctor.com/diseases/leukemia_prolymphocytic.htm] *[[Maladie d'adhésion des lymphocytes]] *'''[[Lymphome]]s :''' **[[Lymphome de Burkitt]] **[[Lymphome de Hodgkin]] **[[Lymphome non-hodgkinien]] *[[Syndrome lymphoprolifératif]] [http://www.wrongdiagnosis.com/a/autoimmune_lymphoproliferative_syndrome/intro.htm] | valign="top" | *[[Leucodystrophie métachromatique]] *[[Syndrome de Morquio]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Morquio%20Syndrome] *[[Sclérose en plaques]] *[[Myélokathexis]] *[[Déficience en actine des neutrophiles]] *[[Syndrome de Nezelof]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Nezelof%27s%20Syndrome] *[[Maladie de Niemann-Pick]] *[[Syndrome d'Omenn]] *[[Ostéopétrose]] *[[Hémoglobinurie paroxysmale nocturne]] *[[Maladie de Vaquez]] *[[Aplasie pure d'érythrocytes]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Pure%20Red%20Cell%20Aplasia%2C%20Acquired] *[[Dysgénèse réticulaire]] [http://www.emedicine.com/med/topic600.htm] *[[Arthrite rhumatoïde]] *[[Maladie de Sandhoff]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Sandhoff%20Disease] *[[Syndrome de Sanfilippo]] *[[Syndrome de Scheie]] [http://www.nlm.nih.gov/medlineplus/ency/article/001246.htm] *[[Syndrome de Shwachman-Diamond]] [http://www.shwachman-diamond.org/] *[[Sialidose]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Sialidosis] *[[Immunodéficience combinée grave]] (SCID) *[[Syndrome de Sly]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Sly%20Syndrome] *[[Lupus érythémateux systémique]] *[[Maladie de Tay-Sachs]] *[[Thalassémie]] *[[Syndrome de Wiskott-Aldrich]] *[[Maladie de Wolman]] (xanthomatose) [http://www.humpath.com/article.php3?id_article=3660] *[[Syndrome hyper IgM lié à l'X]] <!--(XHIGM)--> [http://www.stjude.org/disease-summaries/0,2557,449_2164_6529,00.html] *[[Syndrome lymphoprolifératif lié à l'X]] [http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=X%20linked%20Lymphoproliferative%20Syndrome] |} == Voir aussi == * [[Cellule-souche]] * [[Banque de cellules souches issues du sang de cordon]] * [[Cordon ombilical]] == Liens externes == <!-- ===Généraux=== *[http://www.nationalcordbloodprogram.org/qa/ National Cord Blood Program] — cord blood Q&A *[http://my.webmd.com/content/article/13/1691_50298.htm WebMD] — Can the Umbilical Cord Save Lives? *[http://www.gentlebirth.org/archives/cordIssues.html GentleBirth.org] — Umbilical Cord Issues *[http://www.cordbloodhelp.com/ Cord Blood Help] — Easy to Understand Cord Blood Info ===Maladies traitées par du sang de cordon=== *[http://www.nationalcordbloodprogram.org/patients/ncbp_diseases.htm National Cord Blood Program] — Frequency of patients transplanted with cord blood by disease *[http://www.cordbloodcenter.com/en/01_oc_li.htm Cord Blood Center] — The list of diseases treated with haematopoietic cells transplantation, including autologous cord blood, cord blood from a sibling, autologous bone marrow, and bone marrow from a donor *[http://www.parentsguidecordblood.com/diseases.shtml A Parent's Guide To Cord Blood Banks] — Diseases Treated by Blood Stem Cells *[http://www.cordblood.com/cord_blood_banking_with_cbr/banking/diseases_treated.asp Cord Blood Registry] — Diseases Treated with Stem Cells--> {{Portail médecine}} [[Catégorie:Sang]] [[de:Nabelschnurblut]] [[en:Cord blood]] [[he:דם טבורי]] [[ja:臍帯血]] [[ko:제대혈]] [[pl:Krew pępowinowa]] [[pms:Sangh ëd cordon]]